Ebola spreads

Mali is the latest West African country to go on alert against the Ebola virus, after three cases were reported close to the border with Guinea where 86 people have died. Another six people have died in Liberia, while Sierra Leone has also reported cases.

Senegal has now closed its border with Guinea, and controls are being imposed on people entering Mali’s capital, Bamako.  The virus first appeared in Guinea's remote south-eastern region of Nzerekore, where most of the deaths have happened, but it was not confirmed as Ebola for six weeks, and it has now reached the capital, Conarky.

This is the first known outbreak of the disease in Guinea. Most recent cases have appeared in Uganda and the Democratic Republic of the Congo, and a sign of the alarm it is causing is that Saudi Arabia has suspended visas for Muslim pilgrims from Guinea and Liberia.

The virus is spread easily and kills 25-90% of those it infects. Just as with AIDS when it first appeared, there is no vaccine and no cure. The deadliest outbreak so far came in Congo (then Zaire) in 1976 (pictured), when 280 people died - about 88% of those infected.

Malaria - a glimmer of hope?

Some hopeful signs from a new anti-malaria vaccine.    Preliminary trials had begun in Burkina Faso to test its safety, but it soon became clear that children who had been given the injection were getting a high degree of protection.

The results are described as ‘most encouraging’, and a bigger trial is about to start in Mali.  About 100 different vaccines have been tried against the disease, and this one, developed by the Pasteur Institute in Paris, is only the second to have shown promise.

The Burkina Faso study involved only 45 children, but the incidence of malaria was three or four time lower among those who were given the vaccine.    Eight hundred children will be enrolled in the new trial in Mali.

Malaria still kills around 1 million people a year, 90 per cent of them in Africa, and most of these are young children.  (See also my blogs of 11 April, 30 May, 24 Sept and 21 Oct, 2009.)